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Tirzepatide Dosage Calculator

Compounded or vial tirzepatide in mg to units on an insulin syringe, with the Zepbound 2.5 to 15 mg titration converted for your vial.

Updated · By Niraj Kumar · 3 sources

Medication

What do you want to work out?What do you want to work out?

Vial strength

What does your vial say?What does your vial say?
mg/mL

Printed on the vial label, e.g. "10 mg/mL". Common tirzepatide strengths: 5, 10, 15, 20, 30 mg/mL.

Your dose

mg

Exactly as written on your prescription. 1 mg is 1,000 mcg.

Dose unitDose unit
Draw to25 units0.25 mL on a U-100 insulin syringe
Dose
2.5 mg
2,500 mcg
Concentration
10 mg/mL
Exact volume
0.25 mL
25 units (1 unit = 0.01 mL on a U-100 syringe)
05101520253025 units
Draw 2.5 mg to the 25 units line of a 0.3 mL (30 units) U-100 syringe.
Tirzepatide label doses at 10 mg/mLThe FDA-label titration for Zepbound and Mounjaro, converted for your vial. Follow the schedule your prescriber gave you.
Weekly doseWhenUnitsmL
2.5 mgWeeks 1–4 (starting dose)25 units0.25 mL
5 mgWeek 5 on50 units (over capacity)0.5 mL
7.5 mgAfter 4+ weeks at 5 mg75 units (over capacity)0.75 mL
10 mgAfter 4+ weeks at 7.5 mg100 units (over capacity)1 mL
12.5 mgAfter 4+ weeks at 10 mg125 units (over capacity)1.25 mL
15 mgAfter 4+ weeks at 12.5 mg (maximum)150 units (over capacity)1.5 mL

How do you convert mg to units?

Divide the tirzepatide dose in mg by the vial's mg/mL and multiply by 100. At 10 mg/mL, 2.5 mg is 25 units and 7.5 mg is 75 units. 12.5 and 15 mg need more than 1 mL at that strength, so they are usually given from stronger vials: at 20 mg/mL they are 62.5 and 75 units.

units = dose (mg) ÷ concentration (mg/mL) × 100

This page uses the same method as the GLP-1 Dosage Calculator, which explains each term and assumption in full.

Tirzepatide label doses at 10 mg/mL, in units on a U-100 syringe
Weekly doseWhenUnitsVolume
2.5 mgWeeks 1–4 (starting dose)25 units0.25 mL
5 mgWeek 5 on50 units0.5 mL
7.5 mgAfter 4+ weeks at 5 mg75 units0.75 mL
10 mgAfter 4+ weeks at 7.5 mg100 units1 mL
12.5 mgAfter 4+ weeks at 10 mg125 units1.25 mL
15 mgAfter 4+ weeks at 12.5 mg (maximum)150 units1.5 mL

Worked example

A 2.5 mg tirzepatide dose from a 10 mg vial mixed with 1 mL of bacteriostatic water.

  1. 1Concentration: 10 mg ÷ 1 mL = 10 mg/mL
  2. 2Volume: 2.5 mg ÷ 10 mg/mL = 0.25 mL
  3. 3Units: 0.25 mL × 100 = 25 units
  4. 4Doses per vial: 10 mg ÷ 2.5 mg = 4

Draw to the 25 units line, on a 0.3 mL (30 units) U-100 insulin syringe.

Frequently asked questions

How many units is 2.5 mg of tirzepatide?

50 units at 5 mg/mL, 25 units at 10 mg/mL, 16.7 units at 15 mg/mL, 12.5 units at 20 mg/mL, 8.3 units at 30 mg/mL. See 2.5 mg in units for the syringe to use at each strength.

How many units is a Zepbound single-dose vial?

Every Zepbound single-dose vial holds 0.5 mL, whatever its strength, so the whole vial is the 50-unit line on a U-100 syringe: 2.5 mg is 5 mg/mL, 15 mg is 30 mg/mL. Follow the Instructions for Use that come with the vial.

What is the tirzepatide dose schedule?

The Zepbound label starts at 2.5 mg once a week for four weeks, then 5 mg. Doses can rise in 2.5 mg steps after at least four weeks on each, to maintenance doses of 5, 10 or 15 mg; 15 mg is the maximum. Your prescriber sets your schedule.

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