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Insulin Syringe Units to mg Calculator

Work backwards from the line on a U-100 insulin syringe to the dose in mg or mcg, for any vial strength.

Updated · By Niraj Kumar · 3 sources

Medication

What do you want to work out?What do you want to work out?

Vial strength

What does your vial say?What does your vial say?
mg/mL

Printed on the vial label, e.g. "2.5 mg/mL". Common semaglutide strengths: 1, 2.5, 5 mg/mL.

Your syringe

units

The number on the line the plunger's front edge sits at, on a U-100 insulin syringe.

10 units holds0.25 mg250 mcg at 2.5 mg/mL
Volume
0.1 mL
1 unit = 0.01 mL on a U-100 syringe
Formula
10 ÷ 100 × 2.5
Units ÷ 100 × concentration = dose in mg
05101520253010 units
10 units on a 0.3 mL (30 units) U-100 syringe holds 0.25 mg.
Semaglutide label doses at 2.5 mg/mLThe FDA-label titration for Wegovy and Ozempic, converted for your vial. Follow the schedule your prescriber gave you.
Weekly doseWhenUnitsmL
0.25 mgWeeks 1–410 units0.1 mL
0.5 mgWeeks 5–820 units0.2 mL
1 mgWeeks 9–1240 units (over capacity)0.4 mL
1.7 mgWeeks 13–1668 units (over capacity)0.68 mL
2.4 mgWeek 17 on (usual maintenance)96 units (over capacity)0.96 mL
7.2 mgOnly if prescribed after 4+ weeks at 2.4 mg288 units (over capacity)2.88 mL

How do you convert syringe units to mg?

Divide the units by 100 to get mL, then multiply by the vial's concentration in mg/mL. 20 units from a 2.5 mg/mL vial is 0.2 mL × 2.5 = 0.5 mg. The same 20 units from a 10 mg/mL vial is 2 mg, so the units alone never tell you the dose.

units = dose (mg) ÷ concentration (mg/mL) × 100

This page uses the same method as the GLP-1 Dosage Calculator, which explains each term and assumption in full.

Dose held by common draws on a U-100 syringe, by vial strength
Units drawnAt 2.5 mg/mLAt 5 mg/mLAt 10 mg/mL
5 units (0.05 mL)0.125 mg0.25 mg0.5 mg
10 units (0.1 mL)0.25 mg0.5 mg1 mg
20 units (0.2 mL)0.5 mg1 mg2 mg
25 units (0.25 mL)0.625 mg1.25 mg2.5 mg
30 units (0.3 mL)0.75 mg1.5 mg3 mg
40 units (0.4 mL)1 mg2 mg4 mg
50 units (0.5 mL)1.25 mg2.5 mg5 mg
75 units (0.75 mL)1.875 mg3.75 mg7.5 mg
100 units (1 mL)2.5 mg5 mg10 mg

Worked example

20 units drawn from a vial labelled 2.5 mg/mL.

  1. 1Volume: 20 units ÷ 100 = 0.2 mL
  2. 2Dose: 0.2 mL × 2.5 mg/mL = 0.5 mg

20 units holds 0.5 mg (500 mcg).

Frequently asked questions

How many mg is 10 units?

10 units is 0.1 mL on a U-100 syringe. That is 0.25 mg at 2.5 mg/mL, 0.5 mg at 5 mg/mL and 1 mg at 10 mg/mL. Multiply 0.1 by your vial's mg/mL for your figure.

How many mL is one unit?

On a U-100 insulin syringe, 1 unit is 0.01 mL and 100 units is 1 mL. A 0.3 mL syringe holds 30 units and a 0.5 mL syringe holds 50 units.

Sources

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